The article below may contain offensive and/or incorrect content.
Objective: It is increasingly recognized that trauma victims, particularly Veterans, have co-occurring psychological and physical conditions that impact cognition, especially the domains of sustained attention and executive functioning. Although previous work has generally attempted to isolate the unique cognitive effects of common combat-related comorbidities, less work has been done to examine how these conditions co-occur, and whether unique cognitive signatures accompany certain clinical combinations. Method: To address this gap, we examined how several deployment-related conditions were associated with performance on a well-validated measure of sustained attention (i.e., gradual onset continuous performance task [gradCPT]) and a battery of standard neuropsychological measures in 123 Veterans from the Translational Research Center for TBI and Stress Disorders. Initially, a Principal component analysis was conducted to investigate how comorbid conditions grouped together. Results: Several sustained attention measures from the gradCPT were differentially associated with four unique combinations of trauma-related pathology. Specifically, a somatic component representing the combination of current pain, sleep disturbance, and mild traumatic brain injury was associated with a higher rate of failures of attentional engagement. On the other hand, a comorbid posttraumatic stress disorder (PTSD) and mood disorder component (moodPTSD), as well as a substance use disorder component, were associated with higher rates of inhibitory control failures. Increased attentional instability was associated with moodPTSD as well as an anxiety disorder component. In contrast, the cognitive effects of deployment-related trauma were not observed on standard neuropsychological measures.Conclusion: These findings suggest that unique combinations of trauma-related pathology have dissociable effects on sustained attentional control. (PsycINFO Database Record (c) 2019 APA, all rights reserved)





Departments
Authors
Libraries
Current Articles
- Article Correctness Is Author's Responsibility: Video » Let’s Talk About Eating Disorders with NIMH Grantee Dr. Cynthia Bulik
- Article Correctness Is Author's Responsibility: Scientific Meeting » NIMH Livestream Event: Let’s Talk About Eating Disorders with NIMH Grantee Dr. Cynthia Bulik
- Article Correctness Is Author's Responsibility: Science News » New Experiences Enhance Learning by Resetting Key Brain Circuit
- Article Correctness Is Author's Responsibility: Blog Post » From Brain Mechanisms to Novel Therapies: Understanding and Treating Eating Disorders
- Article Correctness Is Author's Responsibility: Video » GREAT: Helpful Practices to Manage Stress and Anxiety
- Article Correctness Is Author's Responsibility: Video » What are the different types of clinical research?
- Article Correctness Is Author's Responsibility: Blog Post » Enhancing and maintaining a culture of inclusive excellence: The NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program
- Article Correctness Is Author's Responsibility: The snowy countries losing their identity
- Article Correctness Is Author's Responsibility: Science News » Study Identifies Risk Factors for Elevated Anxiety in Young Adults During COVID-19 Pandemic
- Article Correctness Is Author's Responsibility: Keep paying attention to your kids' mental health in this pandemic
- Article Correctness Is Author's Responsibility: Video » What is an MRI?
- Article Correctness Is Author's Responsibility: Video » What is a blood draw?
- Article Correctness Is Author's Responsibility: Video » What is Clinical Research?
- Article Correctness Is Author's Responsibility: Science News » Gene Readouts Contribute To Distinctness of Mental Disorders
- Article Correctness Is Author's Responsibility: Science News » Adaptive screener may help identify youth at risk of suicide
- Article Correctness Is Author's Responsibility: How conspiracy theories undermine people’s trust in COVID-19 vaccines
- Article Correctness Is Author's Responsibility: Curing PTSD with a shot: The new treatments that are changing lives
- Article Correctness Is Author's Responsibility: Feeling disconnected from your partner?
- Article Correctness Is Author's Responsibility: Concept Clearance » Deciphering Neuroimmune Dysfunction in HIV Utilizing Human Cell Derived in vitro and in vivo Systems
- Article Correctness Is Author's Responsibility: Concept Clearance » Understanding and Modifying Temporal Dynamics of Coordinated Neural Activity